The Prayer of St. Ephrem

Author: St. Ephrem

{Making a prostration}

O LORD, Master of my life, grant that I may not be infected with the
spirit of slothfulness and inquisitiveness, with the spirit of ambition and vain talking.

{Making a prostration}

Grant instead to me, your servant, the spirit of purity and of 
humility, the spirit of patience and neighborly love.

{Making a third prostration}

O Lord and King, grant me the grace of being aware of my sins and of not thinking evil of those of my brethren. 
For you are blessed, now and ever, and forever. 

Amen.

Lord Jesus Christ, King of Kings, You have power over life
and death. You know what is secret and hidden, and neither our
thoughts nor our feelings are concealed from You. 
Cure me of duplicity; I have done evil before You. 
Now my life declines from day to day and my sins increase. 
O Lord, God of souls and bodies, You know the extreme frailty of
my soul and my flesh. 
Grant me strength in my weakness, O Lord, and sustain me in my misery. Give me a grateful soul that I may never cease to recall
Your benefits, O Lord most bountiful. 
Be not mindful of my many sins, but forgive me all my misdeeds. 
O Lord, disdain not my prayer - the prayer of a wretched
sinner; sustain me with Your grace until the end, that it may
protect me as in the past. 
It is Your grace which has taught me wisdom; blessed are they who follow her ways, for they shall receive the crown of glory. 
In spite of my unworthiness, I praise You and I glorify You, 
O Lord, for Your mercy to me is without limit. 
You have been my help and my protection. May the name of Your majesty be praised forever. 
To you, our God, be glory. 
Amen.

The Prayer of St. Ephrem is taken in the Byzantine Church during the Liturgy of the Presanctified (Liturgy of Pope St. Gregory the Great, taken by both Catholic and Orthodox alike during this period), during all services of the Divine Office during Lent and at various other times during the day recommended at morning, noon, evening - upon arising and before retiring for the night